Fauci says data from NIH's mix-and-match Covid vaccine booster trials will soon be ready - CNBC

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, gives an opening statement during a Senate Health, Education, Labor and Pensions Committee hearing to discuss the on-going federal response to COVID-19, at the U.S. Capitol in Washington, D.C., May 11, 2021.

Greg Nash | Pool | Reuters

White House chief medical advisor Dr. Anthony Fauci said Tuesday that safety and efficacy data could be available within the next two weeks on pairing a primary regimen of Covid vaccines from one manufacturer with boosters from another.

Though the Centers for Disease and Prevention authorized Pfizer's booster for seniors and the medically vulnerable on Friday, only recipients of Pfizer's first two doses are eligible for their third shot. But the National Institutes of Health are on the verge of concluding trials that mixed boosters and initial doses from Pfizer, Moderna and Johnson & Johnson, Fauci said at a White House Covid briefing.

"As with all things we do, they must be submitted to the FDA for their regulatory approval," Fauci said of the mix-and-match trials. "So you don't want to get ahead of the FDA, but at least that's where the data are right now."

Data on Johnson & Johnson's "mix-and-match study" could be ready within a week, while Pfizer's trial might be completed by mid-October. Moderna's mix-and-match study data are already available, Fauci added.

CNBC Health & Science

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Pfizer and Moderna's vaccines employ mRNA technology to combat Covid, while J&J's uses an adenovirus to bolster the body's immune response. The ability to mix-and-match vaccines and boosters could give vaccine recipients greater flexibility in picking a third shot to strengthen the waning immunity of their initial doses.

Fauci's comments came just days after NIH Director Dr. Francis Collins said the agency was still reviewing the results of combining initial doses and boosters from separate vaccine makers. Collins added that Moderna and J&J were weeks away from the CDC and FDA evaluating their boosters.

The NIH announced the start of its mix-and-match vaccine trials on June 1, which included roughly 150 adults who were vaccinated with either Pfizer, Moderna or J&J. The participants were boosted with a different third dose approximately three to four months after receiving their initial vaccine regimen.

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Fauci says data from NIH's mix-and-match Covid vaccine booster trials will soon be ready - CNBC
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Match Center | September 29 vs. Minnesota United FC - DC United

All attendees will be required to wear a mask when located in an indoor space unless consuming food or beverage while seated.

Fully vaccinated guests (age 3 or older) – meaning two weeks after the second dose in a two-dose series, or two weeks after a single-dose vaccine – will not be required to wear a mask while entering the stadium at any outdoor entry point, or while seated in an outdoor seating location. Unvaccinated guests continue to be required to wear a mask at all times, unless actively eating or drinking in their seat.

All tickets for the match are available through mobile devices; please download your ticket in advance. The easiest place to access your mobile tickets is through the official D.C. United Mobile App.

You can access your tickets by using either the app, or your D.C. United Account Manager. Once logged in, select Manage Tickets and add all of your tickets to either your Apple or GooglePay Wallet. We strongly recommend adding your tickets to your Wallet prior to arriving at the venue, for ease of entry.

Gates open 1.5 hours prior to kickoff. We recommend entering through the gate notated on your digital ticket to eliminate lines upon entry to Audi Field.

For a detailed list of matchday or stadium-related information, refer to the A-to-Z Guide.

To expedite entry into Audi Field, we strongly encourage fans not to bring bags to the stadium. Designated lanes will be set up for fans with bags and fans without bags. If you must bring a bag to the stadium, please see the important info below or visit our Bag Policy page.

Audi Field offers a wide variety of food and beverage options. Visit our Concessions page to view a full menu.

D.C. United fans will have the ability to place an in-stadium mobile order for pick-up to allow all fans to eliminate queuing. Place your order here for pick-up.

At each D.C. United regular season home match, when you pay with ApplePay, get bottled water for just $1! This offer is valid at every concession stand location and through mobile order for pick-up.

Reserve Parking with SpotHero: We recommend booking convenient and affordable parking in advance through SpotHero, the nation's leading parking reservations app.

To reserve your parking spot, visit the Audi Field SpotHero Parking page and book a spot with rates up to 50% off drive-up.

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Match Center | September 29 vs. Minnesota United FC - DC United
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Guess the Starting XI - Match 26 vs. Houston - Eighty Six Forever

Welcome back everyone.

The Vancouver Whitecaps took advantage of an FC Dallas’ team in flux this past weekend. Although it wasn’t a perfect performance, it was a respectable showing that along with the outstanding keeping of Maxime Crepeau, helped push the ‘Caps to all three points as well as 8th position in the Western Conference in terms of points per game.

The heavy lifting is far from over though. On Wednesday, the Whitecaps face another struggling team in Texas, the Houston Dynamo.

The Tim Parker led side has actually been in decent form of late, picking up two wins in their last four matches, albeit against FC Dallas and Austin FC.

Fafa Picault and Darwin Quintero (who is finally playing regular minutes) have been doing most of the offensive work for the Dynamo recently, and for the most part, this has been a team that looks to hit on the counter rather than maintain possession.

Turning to the Whitecaps, the health status of defensive players remains a big question, Florian Jungwirth, Cristian Gutierrez and Erik Godoy were all out of the mix against FC Dallas, so we’ll have to wait and see how they progress in the lead up to this one.

Another question is at the striker spot, where Brian White has been outplaying Lucas Cavallini, which could make things rather challenging when picking a starting XI, especially if Vanni Sartini goes away from two up front, favouring a single striking option.

A final consideration is squad rotation, with travel midweek and a home match on Saturday night, it will be interesting to see how the Whitecaps try to get the most out of their limited squad depth for both of these crucial matchups.

Ok, let’s get on to the rules and standings:

• Predictions will be ‘valid’ if posted HERE (or more accurately, the correct match thread) prior to the lineup being officially announced, usually about an hour before kickoff.
• You receive 1 point for every player you correctly guess to be in the Starting XI. You receive 4 bonus points for correctly predicting all 11 starters.
• You get 5 points for correctly guessing Win/Lose/Draw, this doubles to 10 if you also predict the right score-line along with the result.
• That means, if you correctly predict the Starting XI, Final Score, and Winner, you can earn 25 points!
• At the end of each quarter, the contestants lowest score of that period will be deducted from the cumulative standings.

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Live match blog - Capitals vs KKR 41st Match 2021 - Cricket Insights - ESPNcricinfo

Live Blog

Get your dose of stats, colour and analysis on Kolkata Knight Riders vs Delhi Capitals on ESPNcricinfo's live blog

Eoin Morgan's Kolkata Knight Riders are in a mid-table scrap to make the top four. Rishabh Pant's Delhi Capitals are gunning for the top of the table. Big game coming up.

You'll find ball-by-ball commentary here in English, and here in Hindi. If you're in the USA, you can watch today's game on ESPN+ in English, as well as in Hindi.

New year, new Sharjah?

7.03pm

Morgan: My form not really a concern

6.36pm

R Ashwin is pumped after sending back Eoin Morgan  BCCI

Our commentators paraphrased what Eoin Morgan said at the toss today: 'My form 'not really' a concern. It goes around like a roller coaster, I try to ride it as I can.'

But a duck in a chase like this might be come cause for concern. He hasn't gone into double-digits so far in this IPL season, and in his last ten games (The Hundred included) he hasn't made a single fifty. That sometimes comes with the territory when you bat 4 or later in this format, but Morgan hasn't exactly looked at ease in this period. Remember, he replaced Dinesh Karthik as captain at KKR. Can they go on longer with no runs from the new skipper? At least with Russell out, his current form significantly thins down their batting.

David Hussey said after their last match that Morgan, as captain, will stay in the XI. So things need to turn around quickly as they chase the playoffs.

What's up with Sharjah?

6pm

Sharjah first innings totals before the second phase began  ESPNcricinfo Ltd

You seeing what I'm seeing? Last season, this was the ground to come to and let your batting loose. Look above for the scores made in the first innings at Sharjah last year. Only four innings yielded lower than 150. But more than the scoring itself, it was the promise of coming to a good wicket on a small ground.

That seems to be completely out of the picture this edition. Three first innings so far for a total of eight sixes. None in the first innings of the game today, and more than six wickets have fallen every time. Is this a shot they're taking at neutralising the venue? Shane Warne had suggested three ways he would improve T20 cricket last year, and one of them was to use a Day 4 pitch instead of a "flat road". Some hints here of Sharjah going that way ahead of the T20 World Cup.

Lalit Yadav is going to bowl out, and Rabada is not. This is the new Sharjah. #KKRvsDC

— Snehal Pradhan #MaskUp (@SnehalPradhan) September 28, 2021

Delhi need a franchise record

5.20pm

Delhi defending totals  ESPNcricinfo Ltd

Old school KKR

4.45pm

Lockie Ferguson and Venkatesh Iyer combined to send Shikhar Dhawan back  BCCI

They've traditionally played with six or seven bowling options, most of them spinners. They went away from that strategy at the start of this phase, by starting to use Andre Russell a bit more through the middle overs and playing him as the fifth bowler. His injury, of course, has meant they had to compensate in some way. Southee is a more than handy fifth bowler to have, but the smart use of Venkatesh Iyer has effectively made them a six-bowler team and ensured that there were still two overs left from their spinners past the 14th over. That is bound to have an effect on how the Capitals finish this innings off.

Best spinners in the IPL

4.15pm

Spin bowlers between overs 7-15 since IPL 2020  ESPNcricinfo Ltd

The numbers back up what we've seen every time KKR have had their spinners on in the middle overs - they're simply the best at dragging an innings back. Delhi Capitals' move to have Smith open hasn't resulted in a great start. They've put up their slowest fifty of the season and will continue facing spin for a few more overs now - which means more risks might be forthcoming.

Smith to open?

3.15pm

Steven Smith shapes to play a shot during an intra-squad practice match  Delhi Capitals

With Shaw out injured, it looks like Smith will slot straight into his position as opener. Remember, they were playing only three overseas players after Lalit Yadav had replaced the injured Marcus Stoinis. Smith hasn't had the greatest time in the IPL over the last few seasons, having had indifferent innings with Royals before being sacked from captaincy and then being bought by the Capitals. He's played five innings for 104 runs so far this season, with a strike rate of just under 112. Let's see how the break and a chance to bat in the powerplay affects his game. This is all under the assumption that he will open, of course, because he has looked out of sorts in the middle order and Capitals are unlikely to move Iyer and Pant around.

Smith as opener in T20s: 4 inns, 135 runs, 147.67 strike rate

Final stretch

2.50pm

Varun Chakravarthy practises before the match  BCCI

Kolkata Knight Riders love to play at Abu Dhabi, where only Mumbai Indians have a better IPL record than them. They would have been overjoyed that their first three matches of the second half were held there, and it has showed. With a new combination and approach, they made use of those conditions and nearly made it three out of three before Ravindra Jadeja showed up. Still, they're right back in contention for the playoff, sitting in fourth place. But with eight points, they're tied with three others and this is another opportunity to break that deadlock. We'll have to wait and see if Andre Russell will be available for that after he went off with a hamstring injury against Chennai. Although with Tim Southee being handed a cap, that looks unlikely.

Delhi Capitals are far more comfortably placed, all but through to the playoffs with 16 points on the board and four games to go. They'll be hoping players like Prithvi Shaw, Rishabh Pant, and Shimron Hetmyer get big runs in the four matches left.

Varun Shetty is a sub-editor at ESPNcricinfo

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WWE Raw results, recap, grades: Big E survives championship cage match with Bobby Lashley on loaded show - CBSSports.com

Fans wanting good in-ring action on Monday night's edition of WWE Raw got their wish. There were outstanding matches up and down the card, including a pair of matches for the WWE championship, with Big E defending the belt against Bobby Lashley.

Big E and Lashley opened the show with a match for the title only to see The Hurt Business reunite in support of Lashley, leading to a no-contest. WWE made things right in the main event, having Lashley and Big E settle things inside a steel cage, resulting in a dramatic win for Big E to cap off a great night of action on the final Raw before the WWE Draft begins on Friday Night.

CBS Sports was with you all night with recaps and highlights of all the action from Heritage Bank Center in Cincinnati, Ohio.

Big E and Bobby Lashley go to war twice in one night

WWE Championship – Big E (c) vs. Bobby Lashley ended in a no-contest. The title match kicked off the show, as was promised during Sunday night's Extreme Rules card. Lashley stayed in command of the match for a long stretch, with Big E only getting small hope spots only to be cut off by the power and aggression of Lashley again and again. As Big E started to make his comeback, Cedric Alexander and Shelton Benjamin came to ringside in Hurt Business gear, apparently reforming the group with MVP sidelined with a knee issue. Kofi Kingston and Xavier Woods ran in to make the save, leading to a pin break after a Lashley spear and forcing the referee to call for the bell. WWE official Adam Pearce announced that Big E and Lashley would settle their differences later in the night in a steel cage match.

WWE Championship – Big E (c) def. Bobby Lashley via pinfall in a cage match to retain his title. Lashley attacked Big E before the champion could get into the cage. Lashley drove Big E into the barricade and into the outside of the cage several times to get a huge advantage before the match even began. After a commercial break, both men were finally in the cage to begin the match. Big E tried to get a quick start by countering a Lashley charge but Lashley quickly took control back before starting to attempt to leave the cage to score the win. Big E managed to knock Lashley from the cage before nearly climbing out himself when The Hurt Business ran in to knock Big E back. The New Day ran in to slam the cage door on Lashley's head before brawling with Benjamin and Alexander, with Kingston leaping off the cage and onto the Hurt Business members. Officials ejected all four men from ringside to leave it as a one-on-one match again. Lashley repeatedly tried to walk out of the cage only to have Big E grab his wrist. Lashley kicked out of a Big Ending once, but not a second one delivered off the second rope as Bg E retained his title. After the match, Drew McIntyre arrived to issue a silent challenge to Big E as the show went off the air.

In what was a very good episode of Raw, Lashley and Big E delivered the goods in both the opener and the main event. Big E needed a clean win to really establish himself as the true champion and that's exactly what happened. Big E now has three pinfalls over Lashley, which should be enough to move on, though McIntyre isn't the most exciting option. Still, all credit to Big E and Lashley for their work over the night. Grade: A

What else happened on WWE Raw?

• Angel Garza def. Erik via pinfall after hitting a Wing Clipper.
• 24/7 Championship -- Reggie (c) vs. Ricochet ended in a no-contest after interference from Drew Gulak and R-Truth. 24/7 rules were suspended during the match, so the attack was a set-up to try and allow Akira Tozawa to win the belt from Reggie, but Reggie was able to escape the ambush with his title.
• Keith Lee def. Akira Tozawa via pinfall after the Big Bang Catastrophe. Lee was again announced as Keith "Bearcat" Lee.
• United States Championship -- Damian Priest (c) def. Sheamus via pinfall with Reckoning. As expected, this was a brutal match that saw some big moves, such as a Sheamus White Noise from the ring apron through a table at ringside. After more tables, kendo sticks and steel chairs, Priest was able to get the win and retain his title in a match that left both men badly bruised.
• Jinder Mahal, Veer & Shanky def. Jeff Hardy, Mustafa Ali & Mansoor via pinfall after Veer hit Ali with a lariat.
• Karrion Kross def. Jaxson Ryker via submission with the Kross Jacket.
• AJ Styles def. Riddle via pinfall after a Styles Clash. Randy Orton was out for the week, leaving Riddle without support, but Styles was able to win clean without interference from Omos. Omos did, however, hit Riddle with a chokeslam after the match.
• Raw Women's Championship -- Charlotte Flair (c) def. Doudrop via pinfall after hitting Natural Selection. Doudrop seemed to have the match in hand when she was distracted by Eva Marie's music, allowing Flair to score the win and retain her title. Eva Marie cut a promo in the ring after the match only to have Shayna Baszler brutally attack her, choking her out before stomping on her arm.
• Goldberg vowed revenge on Bobby Lashley. Goldberg said he hopes to get lucky enough to kill Lashley for putting his hands on his son.

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Hong Kong inspired Memory Match game of North Bay raises funds for the Y - BayToday.ca

A Memory Match Game created by Sira and Kate Cotter, twin 13-year old girls, has raised  $2,700 for the North Bay YMCA.

The girls got inspiration from a game they played with images from Hong Kong.

Sira and Kate were planning to do a charity fundraiser and when they saw the YMCA was raising funds for My Y is Resilient. They thought the game would help support tourism in North Bay.

See: Local jobs, daycare spaces at risk as YMCA seeks $1M from community

“We wanted to help the Y because of the great memories we have from our time at Camp Tillicum. We can't wait to get back to Canada next summer to take the leadership course so that we can be leaders at future Y camps.” said Kate.

“The Y is a really important part of our community. We were worried that the Y wouldn't be there for other children and thought that we should help. Making the game was fun and we got to meet so many wonderful people who helped us to make and sell the game.” said Sira.

See: Camp Tillicum’s future is rooted in its past

The games were printed by See More Graphics.  Games were sold for $20.

“After being approached by Kate and Sira Cotter for help with the memory match game, we wanted to help in any way we could," said Marc Daigle. "See More Graphics helped the project by designing and producing the game for the two young ladies and we’re glad to do our part in order to make the game as big of a success as it was.” 

“Their initiative embraces the values of the YMCA and demonstrates that both our YMCA and our community are in good hands with leaders like them,”said Helen Francis, President, YMCA of Northeastern Ontario.

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Unlock United Club access and more with easy Air Canada status match offer - The Points Guy

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