A medical worker administers a dose of the "Comirnaty" Pfizer-BioNTech COVID-19 vaccine in a vaccination center in Paris as part of the coronavirus disease (COVID-19) vaccination campaign in France, May 12, 2021. REUTERS/Gonzalo Fuentes
A growing number of countries are looking at switching to different COVID-19 vaccines for second doses amid supply delays and safety concerns that have slowed their vaccination campaigns. read more
Several medical studies to test the efficacy of switching COVID-19 vaccines are under way. read more
The following are countries that are weighing, or have decided to adopt, such a solution:
CANADA
* Officials said in May that people who were inoculated with AstraZeneca's (AZN.L) COVID-19 shot may be offered a second dose of another vaccine, a move based on supply concerns as well as the rise in incidence of rare blood clots linked to first doses produced by the Anglo-Swedish drugmaker.
CHINA
* Chinese researchers in April were testing the mixing of COVID-19 vaccine doses developed by CanSino Biologics (6185.HK), and a unit of Chongqing Zhifei Biological Products (300122.SZ), according to clinical trial registration data.
* China's top disease control official said on April 12 the country was "formally considering" mixing COVID-19 vaccine doses developed with different technologies to boost their efficacy.
FINLAND
* Finland's Institute of Health and Welfare said on April 14 that recipients of a first dose of AstraZeneca's vaccine who are aged under 65 may get a different shot for their second dose, as authorities warned about delays to the country's rollout. read more
FRANCE
* France's top health advisory body Haute Autorite de la Sante (HAS) recommended in April that people under 55 injected with a first shot of the AstraZeneca vaccine should receive a second dose with a so-called messenger RNA vaccine, although dose-mixing has not yet been evaluated in trials. read more
NORWAY
* Norway said on April 23 it would offer those who have received a dose of the AstraZeneca vaccine an injection with an mRNA vaccine as their second dose. read more
SOUTH KOREA
* South Korea said on May 20 it would run a mix-and-match trial of COVID-19 vaccines, mixing AstraZeneca doses with those developed by Pfizer and other drugmakers. read more
SPAIN
* Spanish Health Minister Carolina Darias said on May 19 the country would allow people under 60 years old, who have received a first dose of AstraZeneca's vaccine, to receive a second dose of either the AstraZeneca shot or Pfizer's (PFE.N) vaccine. read more
* A study on mixing COVID-19 vaccines, run by Spain's state-backed Carlos III Health Institute, found that giving a dose of Pfizer's shot to people who have already received a first shot of AstraZeneca's vaccine is safe and highly effective, preliminary results showed on May 18. read more
SWEDEN
* Sweden's health agency said on April 20 that people under 65 years of age, who have had one shot of AstraZeneca's vaccine, would be given a different vaccine for their second dose.
UNITED KINGDOM
* Britain said in January it would allow people to be given a different vaccine for a second dose on extremely rare occasions, for example if the first vaccine was out of stock. read more
* The first findings of an Oxford University-led study released on May 12 found that people who received Pfizer's vaccine followed by a dose of AstraZeneca's, or vice versa, were more likely to report mild or moderate common post-vaccination symptoms than if they received two of the same type. https://bit.ly/3fraZz9
* Novavax (NVAX.O) said on May 21 it would take part in a mix-and-match COVID-19 vaccine trial to test the use of an additional vaccine dose from a different producer as a booster. The trial will start in June in the United Kingdom
UNITED STATES
* In January, CNBC reported the U.S. Centers for Disease Control and Prevention (CDC) had updated its guidance, allowing a mix of Pfizer/BioNTech's (22UAy.DE) and Moderna's (MRNA.O) shots with a gap of at least 28 days between the two inoculations, and only for "exceptional situations".
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Factbox: Countries weigh 'mix and match' COVID-19 vaccines - Reuters
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